Detection of Clostridium difficile toxin: comparison of enzyme immunoassay results with results obtained by cytotoxicity assay |
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| Authors: | Musher Daniel M Manhas Atisha Jain Pranav Nuila Franziska Waqar Amna Logan Nancy Marino Bernard Graviss Edward A |
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| Institution: | Medical Service (Infectious Disease Section), Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas 77030, USA. daniel.musher@med.va.gov |
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| Abstract: | Several kinds of laboratory techniques are available to detect Clostridium difficile toxin in fecal samples. Because questions have been raised about the reliability of immunoassays compared to the accepted standard, cytotoxicity assay, we studied three enzyme immunoassays (EIAs) and one rapid EIA, which demonstrated relatively good sensitivities and specificities compared to cytotoxicity assay. |
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