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泻心汤配伍沉淀物的药效学研究
引用本文:李建荣,张广平,吴兰生,严梅桢,宋红月. 泻心汤配伍沉淀物的药效学研究[J]. 中国实验方剂学杂志, 2004, 10(5): 27-30
作者姓名:李建荣  张广平  吴兰生  严梅桢  宋红月
作者单位:中国中医研究院中药研究所,北京,100700
基金项目:国家中医药管理局中医药科学技术研究专项资金(0 2 0 32 957)
摘    要:目的 :观察泻心汤配伍后产生沉淀物的药效。方法 :在大鼠幽门结扎与阿斯匹林复合溃疡模型、大鼠角叉菜胶气囊法所致炎症模型上比较其煎液、上清液和沉淀物的药效 ;比较三者对金黄色葡萄球菌及大肠杆菌临床分离株的体外抑菌效果。结果 :泻心汤沉淀物的抗溃疡和抗炎作用与其煎液相似。结论 :泻心汤配伍后产生的沉淀物具有和其煎液相似的生物活性

关 键 词:泻心汤  沉淀物  抗溃疡  抗炎  抗菌
文章编号:1005-9903(2004)05-0027-04
收稿时间:2004-01-18
修稿时间:2004-01-18

Pharmacodvnamic Study on the Sediments that Produced by Matching of Herbs in Xiexintang
LI Jian-rong,ZHANG Guang-ping,-WU Lan-sheng,YAN Mei-zhen,SONG Hong-yue. Pharmacodvnamic Study on the Sediments that Produced by Matching of Herbs in Xiexintang[J]. China Journal of Experimental Traditional Medical Formulae, 2004, 10(5): 27-30
Authors:LI Jian-rong  ZHANG Guang-ping  -WU Lan-sheng  YAN Mei-zhen  SONG Hong-yue
Affiliation:Institute of Chinese Materia Medica,China Academy of Traditional Chinese Medicine,Beijing 100700
Abstract:Objective: To observe the Pharmacological effect of the sediments produced by matching of Herbs in Xiexintang.Method:Gastric ulcer model of rat induced by polorous ligation with aspirin administration model of rat induced by carragreenin were used.Bactriostatic effect was evaluated by using gold staphylococcus and Escherichia.Effects of Xiexin decoction,the supemate and the sediments of the decoction were compared by using the above mentioned models and bacterial cultuer.Result:The effects of the sediments of Xiexin decoction and that of the Xiexin decoction are similar.Conclusion:Biological activity of the sediments that produced by matching of herbs of Xiexintang decocting and that of the Xiexin decoction are the same.
Keywords:Xiexin decoction  sediments  anti-infection  anti-ulcer  bacteriostasis
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