Identification of dopamine-containing cell bodies in the dorsal and median raphe nuclei of the rat brain using tyrosine hydroxylase immunochemistry |
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| Authors: | Michael E. Trulson M.Samuel Cannon Joachim D. Raese |
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| Affiliation: | 1. Department of Anatomy, College of Medicine, Texas A and M University, College Station TX 77843 USA;2. The Schizophrenia Research Center, Southwestern Medical School and Veterans'' Administration Medical Center, Dallas, TX 75216 USA |
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| Abstract: | Using immunohistochemical methods with antibodies specific to tyrosine hydroxylase, we examined the distribution of dopaminergic cells in the dorsal and median raphe nucleus of the rat brain. Although dopamine-containing cell bodies were previously thought to be almost exclusively confined to the substantia nigra pars compacta, ventral tegmental area, and tuberoinfundibular system, we found numerous cell bodies which stained for tyrosine hydroxylase in the dorsal and median raphe nuclei. |
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| Keywords: | Tyrosine hydroxylase Dorsal raphe Median raphe Serotonin Immunohistochemistry Rat brainstem |
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