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Bisphosphonate osteonecrosis of the jaw—a literature review of UK policies versus international policies on bisphosphonates, risk factors and prevention
Authors:Vinod PatelNiall M.H. McLeod  Simon N. RogersPeter A. Brennan
Affiliation:a Oral & Maxillofacial Surgery, Guy's Hospital, London, UK
b Oral & Maxillofacial Surgery, Queen Alexandra Hospital, Portmouth, UK
c Regional Maxillofacial Unit, University Hospital Aintree, Liverpool, UK
Abstract:There has been an exponential rise in the literature of osteonecrosis and its complications in patients taking bisphosphonate drugs. Despite this increase, there is little evidence-based publications on how best to manage this complication. In this article (the first of two on bisphosphonate related jaw complications), we compare the guidelines produced by national specialist medical associations and expert panels on the prevention of bisphosphonate osteonecrosis of the jaws and review the evidence behind these guidelines.
Keywords:Bisphosphonate   Osteonecrosis   Jaw bone   Risk factors   Prevention
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