| 过敏性鼻炎的遗传学研究进展 |
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| 引用本文： | 赵延明,张罗.过敏性鼻炎的遗传学研究进展[J].首都医学院学报,2013(6):808-813. |
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| 作者姓名： | 赵延明 张罗 |
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| 作者单位： | [1]首都医科大学附属北京同仁医院耳鼻咽喉头颈外科,北京100730 [2]教育部耳鼻咽喉头颈外科重点实验室,北京市耳鼻咽喉科研究所,北京100005 |
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| 基金项目： | 国家杰出青年科学基金（81025007）;国家自然科学基金（30872846）;北京市自然基金（7102030）;北京市卫生系统高层次卫生技术人才学科带头人（2009-02-007）和鼻病研究北京市重点实验室2012年阶梯计划项目（Z121107009212032）. |
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| 摘 要： | 近年来过敏性鼻炎在全世界的发病率呈上升趋势,已成为各国医疗支出的重要负担.有关过敏性鼻炎的病因、发病机制及治疗等方面尚有很多问题亟待解决,而过敏性鼻炎的遗传学研究是发现新的致病机制、指导临床预防及探索药物靶向治疗途径的有效手段.本文旨在对过敏性鼻炎的遗传学研究方法和研究进展作一概述.
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| 关 键 词： | 过敏性鼻炎 基因 遗传学 |
Progress in genetic study on allergic rhinitis |
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| ZHAO Yanming,ZHANG Luo.Progress in genetic study on allergic rhinitis[J].Journal of Capital University of Medical Sciences,2013(6):808-813. |
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| Authors: | ZHAO Yanming ZHANG Luo |
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| Institution: | 1. Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; 2. Key Laboratory of Otorhinolaryngology Head and Neck Surgery, Ministry of Education of China, Beijing Institute of Otolaryngology , Beifing 100005, China) |
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| Abstract: | Allergic rhinitis is a disease of high prevalence and has exhibited a fairly rapid upward trend all over the world. This high prevalence translates into a high cost to society. There are still some unanswered questions related to the etiology, pathogenesis and treatment of allergic rbinitis. The genetic study of allergic rhinitis is an effective way to detect novel mechanism, prevention and personalized drug therapy in allergic rhinitis individuals. The aim of this review is to elaborate on the methods and progress of the genetic study on allergic rhinitis. |
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| Keywords: | allergic rhinitis gene genetics |
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