|
|||||
|
|
Insulin-like growth factor binding protein 2 promotes ovarian cancer cell invasion |
|
| Authors: | Lee Eun-Ju Mircean Cristian Shmulevich Ilya Wang Huamin Liu Jinsong Niemistö Antti Kavanagh John J Lee Je-Ho Zhang Wei |
| Affiliation: | (1) Departments of Pathology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas 77030, USA;(2) Department of Gynecologic Medical Oncology, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, Texas 77030, USA;(3) Molecular Therapy Research Center, Samsung Medical Center, Seoul, 135–710, Korea;(4) Institute of Signal Processing, Tampere University of Technology, Tampere, Finland |
| Abstract: | BackgroundInsulin-like growth factor binding protein 2 (IGFBP2) is overexpressed in ovarian malignant tissues and in the serum and cystic fluid of ovarian cancer patients, suggesting an important role of IGFBP2 in the biology of ovarian cancer. The purpose of this study was to assess the role of increased IGFBP2 in ovarian cancer cells. |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |