微电极导向多靶点毁损手术治疗帕金森病

目的：总结微电极导向多靶点毁损手术治疗帕金森病的初步经验。方法：应用微电极导向技术对24例临床表现为混合型的帕金森病患进行了多靶点毁损手术治疗，在术毕、术后1周进行临床疗效观察，统一帕金森病评定量表（UPDRS）综合评分对比，并观察跟随1－17个月。结果：全部患肢体活动灵活性、震颤在术毕即得到显；随访1－17个月后症状维持稳定，术前和术后UPDRS评分显提高。结论：微电极导向多靶点毁损手术治疗帕金森病是切实可行的方法。

Microelectrode-guided sterotactic surgery of multi-targets lesion for Parkinson's disease

Objective: : To summarize th e preliminary experience in microelectrode-guided multi-targets lesion sterota ctic surgery for advanced Parkinson's disease. Methods: The hea ling effects of 24 patients with rigidity and tremor in unilateral and/or bilate ral extremities were observed and evaluated according to the Unified Parkinson's Disease Rating Scale (UPDRS) one week before and after microelectrode-guid ed sterotactic surgery of multi-targets lesion. Follow-up ranged from 1 to 17 months.Results: Following surgery,rigidity tremor and poor reci procal movements were significantly improved. The patients obtained good results during 1-17 months follow-up after surgery. Preoperative and postoperative UP DRS score improved significantly. Conclusion: Microelectrode-g uided sterotactic surgery of multi-targets lesion is safe and feasible for adva nced Parkinson's disease.