The percentage and clinical correlates of alexithymia in stable patients with schizophrenia |
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Authors: | Yi Yun Huang Yuanyuan Jiang Rui Chen Qiang Yang Mingzhe Li Hehua Feng Yangdong Feng Shixuan Zhou Sumiao Zhang Lixin Ning Yuping Li Zezhi Wu Fengchun |
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Affiliation: | 1.Department of Psychiatry, The Affiliated Brain Hospital of Guangzhou Medical University, 36 Mingxin Rd, Liwan District, Guangzhou, 510370, China ;2.Department of Psychiatry, Qingdao Mental Health Center, Qingdao, China ;3.Department of Psychiatry, The Brain Hospital of Guangxi Zhuang Autonomous Region, Guangxi, China ;4.Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China ; |
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Abstract: | Alexithymia is a common, but less-recognized affective deficit in patients with schizophrenia. To date, no definitive conclusions have been drawn about the relationship between alexithymia and the clinical symptoms or their clinical correlates, particularly in stable patients with schizophrenia. The purpose of this study was to investigate the link between alexithymia and psychopathological symptoms, as well as any associated correlates, in stable patients with schizophrenia. A total of 435 Chinese patients with schizophrenia were recruited. The Positive and Negative Symptoms Scale (PANSS) was used to evaluate each patient’s psychopathological symptoms. The Toronto Alexithymia Scale (TAS-20) was used to measure alexithymia. The percentage of alexithymia was 35.2% in stable patients with schizophrenia. Compared to non-alexithymia patients, patients with alexithymia had higher PANSS total scores, negative subscores, depressive subscores, and cognitive subscores (all p < 0.05). Multivariate regression analysis revealed that the following variables were positively associated with TAS-20 total scores: PANSS negative subscores (β = 0.274, t = 3.198, p = 0.001) and PANSS depressive subscores (β = 0.366, t = 2.500, p = 0.013). Education years (β = – 0.453, t = – 2.824, p = 0.005) was negatively associated with TAS-20 total scores. Our results suggest that the percentage of alexithymia was relatively higher in stable patients with schizophrenia. Education levels, negative symptoms, and depressive symptoms were independently associated with alexithymia in this specific population. |
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