脑康泰胶囊对脑缺血及痴呆小鼠学习记忆的影响

目的：观察脑康泰胶囊对小鼠学习记忆能力的影响。方法：采用脑缺血再灌注损伤及Ｄ－半乳糖所致痴呆小鼠模型。结果：脑康泰胶囊显著增强脑缺血再灌注损伤模型小鼠被动和主动学习能力，但对血液ＭＤＡ、ＭＡＯ和ＳＯＤ含量影响不显著；脑康泰除明显增强老年痴呆小鼠主动学习和空间分辨的能力外，还能显著降低小鼠血液中ＭＤＡ和ＭＡＯ水平。结论：脑康泰胶囊对改善上述模型小鼠学习记忆能力有显著促进作用。

Influences of Naokangtai capsule to the memory of mice with cerebral ischemia reperfusion injury and senile dementia

OBJECTIVE:To investigate the effect of Naokangtai capsule on the abilites of learning and memory of mice.METHODS:The models of cerebral ischemia reperfusion injury and senile dementia mice caused by D galactose were used.RESULTS:Naokangtai capsule improved the abilites of active and passive learning and memory remarkedly in the model mice with cerebral ischemia reperfusion injury,but there was no influence to the contents of MDA,SOD and MAO.In senile dementia mice induced by D galactose,Naokangtai capsule possessed obvious effects of improving memory and spatial resolution and decreased contents of MDA and MAO in blood significantly.CONCLUSION:Naokangtai capsule can promote ability of learning and memory of mice effectively.