米非司酮与利凡诺联合用于中孕引产72例临床观察

目的探讨米非司酮与利凡诺联合用于中期妊娠引产的临床效果。方法选择144例要求终止妊娠的中孕妇女随机分为观察组与对照组。观察组在行经腹利凡诺羊膜腔内注射术前,给予米非司酮150mg分次口服;对照组单用利凡诺100mg羊膜腔内注射。观察并记录自注药至宫缩开始时间,由宫缩开始到胎儿娩出时间,胎盘娩出后检查胎盘胎膜完整性,软产道有无损伤。结果两组中孕妇女均一次穿刺注药引产成功。对照组中有4例出现宫缩乏力,给催产素加强宫缩引产成功。观察组未出现类似情况。观察组与对照组从注药到宫缩开始时间、从宫缩开始到胎儿娩出时间、胎盘胎膜残留及宫颈撕裂伤比较均有差异性。观察组从注药到宫缩开始时间、从宫缩开始到胎儿娩出时间明显缩短(P<0.01),胎盘胎膜残留及宫颈撕裂伤的发生率均较对照组明显减少(P<0.01)。对照组51例未行清宫术,观察组66例未行清宫术,胎盘胎膜残留明显减少。对照组宫颈撕裂伤3例,3例宫颈撕裂伤均未静滴催产素,宫颈撕裂伤与催产素无关。观察组无宫颈撕裂伤。结论米非司酮与利凡诺联合用于中期妊娠引产,使引产总产程缩短,减少胎盘胎膜残留,是一种值得推广的中孕引产方法。

Mifepristone and Rivanol joint for 72 cases of induced abortion in pregnant clinical observation

Objective To study the effects of mifepristone and rivanol joint use in the medium-term clinical effects of pregnancy induced labor. Methods 144 cases to terminate the pregnancy in pregnant women were randomly divided into observation group and control group. Observer Group in passing through the abdominal cavity Rivanol injection preoperatively, at times to 150rag of oral mifepristone, the control group alone Rivanol 100mg amniotic injection. Observed and recorded since the beginning of injection to the contraction time, by the contraction to the delivery time for the fetus, the placenta after delivery to check the integrity of placental membranes, whether the soft birth canal injury. Results The two groups in both the first puncture injection successfully induced labor in the control group there were four cases of uterine atony appears to strengthen the uterine oxytocin induction of labor success. Observer Group similar situation does not appear The observation group and control group from the injection to the starting time of contraction, from contraction to the delivery time for the fetus, placenta membrane and cervical laceration compared residues are differences, the observation group to the contraction from the injection start time, from the beginning to the contraction of fetal delivery time was significantly shorter （P〈0.01）, placenta and fetal membrane residue incidence of cervical laceration than those in the control group decreased significantly （P〈0.01 ） 51 cases of the control group did not undergo uterine surgery, 66 cases of the observation group did not undergo uterine surgery, placenta membrane residues decreased significantly. Control group, three cases of cervical laceration, 3 cases of cervical laceration were not intravenous infusion of oxytocin, cervical laceration and oxytocin are not relevant to the observation group no cervical lacerations.Enter here Conclusion Mifepristone and Rivanol joint mid-term pregnancy for induction of labor, so that the total production process to shorten the induction of labor to reduce the placental membrane residues, reducing induction of postpartum hemorrhage and infection occurrence, is a worthy method of induced abortion in the pregnancy.