Acute colonic pseudo-obstruction (Ogilvie's syndrome) in pneumococcal meningo-encephalitis treated with neostigmine |
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Authors: | Ould-Ahmed M de Saint-Martin L Ansart S Renault A Boles J-M |
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Affiliation: | Service de réanimation médicale, centre hospitalier universitaire Cavale-Blanche, 29609 Brest, France. mehdi.oa@wanadoo.fr |
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Abstract: | We report the case of a 71-year-old man with acute colonic pseudo-obstruction that complicates a pneumococcal meningo-encephalitis. After 48 h of conservative management with nothing by mouth, nasogastric suction, fluid and electrolyte correction, withdrawal of any anticholinergic agents, a pharmacological approach with 2 mg of neostigmine was successful in intensive care unit. This treatment was effective in over 80% of patients of recent reports. Neostigmine might be considered as first-line therapy in patients who do not have major contraindications to its use, because of less frequent iatrogenic risk than colonoscopic decompression or surgery. |
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