双枕角穿刺尿激酶联合自体血清灌注治疗脑室出血的临床分析

目的 探讨腰大池持续外引流结合双枕角穿刺尿激酶联合自体血清灌注治疗脑室出血的临床疗效.方法将106例脑室出血患者随机分为治疗组和对照组,治疗组53例行双枕角穿刺尿激酶联合自体血清灌注治疗,对照组53例行双侧枕角穿刺尿激酶灌注治疗,后期均行腰大池持续外引流.结果对照组有效39例(73.6%),无效6例(11.3%),死亡8例(15.1%),72h脑室积血消失率77.4%;治疗组有效47例(88.7%),无效4例(7.5%),死亡2例(3.8%),72h脑室积血消失率92.5%;两组比较差异均有统计学意义(均P<0.05).结论双枕角穿刺尿激酶联合自体血清灌注治疗脑室出血效果优于单纯双枕角穿刺尿激酶灌注,是一种更有效的治疗方法.

Clinical analysis of autologous serum injection cobined with urokinase through continuous drainage in lumbar occipital angle on encephalocoele hemarrage patients

Objective To study the clinical effects of autologous serum injection combined with urokinase through continuous drainage in lumbar occipital angle on encephalocoele hemarrage patients. Methods 106 cases of encephalocoele hemarrage were randomly allocated to treatment group (n = 53) and control group (n = 53). Urokinase injection were applied to both group through double occipital angle puncture, and additional autolagous serum were given to these in treatment group. Results There were 39 cases(73.6%) with effectiveness, 6 cases(11.3%) without any effects and 8 (15.1%) deaths in the control group and in the treatment group, these were 47 (88.7%), 4 (7.5%) and 2 (3.8%) (P < 0.05). The ratio of Hemarrage disappearing in both group are 77.4% and 92.5% respectively (P < 0.05). Conclusion Autologous serum injection combined with tradition treatment is a better alternative.