营养干预对肥胖伴代谢综合征人群相关指标的影响

目的观察营养干预对肥胖伴代谢综合征人群体成分、血生化指标及血压的改善作用，探讨健康减重的方式。方法体质指数（BMI）≥28．0kg／m^2；男性腰围≥85cm、女性腰围≥80cm；伴有血脂、血压及血糖任两项检查异常的体检肥胖伴代谢综合征患者40例自愿参与本研究，观察营养干预两个月后参与者干预前后体成分、血脂、血糖、血压等指标的变化。统计分析采用SPSS18．0统计软件，计量资料以x^-±s表示，干预前后对比采用配对t检验。结果营养干预进行2个月后参与者体重、体脂肪量、BMI、内脏脂肪面积和腰臀比与干预前比较差异有统计学意义（t=17．02、11．07、5．11、10．35、9．58，P〈0．05）；营养参与者的干预前和干预后丙氨酸氨基转移酶、天冬氨酸氨基转移酶、胆固醇、三酰甘油、空腹血糖、收缩压和舒张压比较差异均有统计学意义（t=2．87、2．91、3．33、2．24、2．56、5．74、6．99，P〈0．05）。结论营养干预的方法通过减重，降低体内脂肪含量，对肥胖患者的血压、血糖和血脂异常有着明显的改善效果，从而降低因肥胖造成的胰岛素抵抗。

The impact of netrition intervention for obese patients with metabolic syndrome indicators

Objective To explore the effects of nutritional intervention on body composition, blood biochemical parameters and blood pressure of overweight adults with metabolic syndrome. Methods Forty overweight adults with metabolic syndrome （ body mass index （ BMI ） 〉 28.0 kg/m^2, waist circumference ≥ 85 cm（for male）or ≥80 cm（for female） ）participated in this investigation. Changes of serum lipid profiles, blood glucose, blood pressure and other indicators were compaired before and after 2-months＇ intervention. SPSS 18.0 Software was used for data analysis. Results After two months＇ nutritional intervention, body weight, body fat, BMI, visceral fat area and waist hip ratio were significantly improved （t = 17.02, 11.07, 5. 11, 10. 35, 9.58; P 〈 0.05 ） . The glutamic-pyruvic transaminase, glutamic-oxalacetic transaminease, cholesterol, triacylglycerol, fasting blood-glucose, systolic blood pressure and diastolic blood pressure were also significantly improved after nutrition intervention（ t = 2. 87,2. 91,3.33,2. 24,2.56,5.74, 6. 99 ; P 〈 0. 05 ）. Conclusion Nutrition intervention may contribute to improved levels of blood pressure, blood glucose and serum lipid profiles of obesity individuals through body weight and body fat control and lead to reduced insulin resistance caused by obesity.