中国成人腰围身高比与血脂异常的关系

目的研究中国成人腰围身高比（WHtR）与血脂异常的关系，并提出WHtR预测血脂异常的适宜截点。方法采用整群随机抽样，对2008至2009年度在4个全国性体检机构进行健康查体的221270名城市人群，测量其身高、体重、腰围（WC），计算体质指数（BMI）和WHtR，并检测血脂四项。采用受试者工作特征曲线（ROC）比较曲线下面积，计算不同水平肥胖指标预测血脂异常的灵敏度和特异度，通过约登指数最大值找到适宜截点。结果WHtR在高TC血症、高TG血症及高LDL—C血症的ROC曲线下面积最大，其次为WC及BMI；WHtR最佳截点范围男性为0．49～0．50，女性为0．47～0．49；WC男性为83～85enl，女性为73～76em；BMI男性为24～25kg／m^2，女性为22～23kg／m^2。结论WHtR筛查不同类型的血脂异常优于WC和BMI，推荐适宜截点男女性均为0．5。

Waist-to-height ratio as a predictor of dyslipidemia for Chinese adults

Objective To explore the association between waist-to-height ratio （WHtR） and dyslipidemia in Chinese adults and to find out an optimal threshold of WHtR for predicting dyslipidemia. Methods A total of 221 270 adults from 4 health checkup centers nationwide were selected by using cluster random sampling method. Height, body weight, waist circumference （ WC ） , total cholesterol （ TC ）, triglyceride （ TG ）, high-density lipoprotein cholesterol （ HDL-C ） and low-density lipoprotein cholesterol（LDL-C） were measured. Body mass index （BMI） and WHtR were then calculated. The area under the receiver operating characteristic curve（ AUC ） was analyzed and optimal cutoffs were estimated by maximizing the sums of sensitivity and specificity. Results WHtR showed the largest AUCs in the participants with higher TC, TG and LDL-C, followed by increased WC and BMI. In male and female, the optimal thresholds of WHtR, WC and BMI for predicting dysfipidemia were 0.49-0. 50 and 0. 47-0. 49,83-85 and 73-76 cm, and 24-25 and 22-23 kg/m^2, respectively. Conclusion WHtR may be superior to WC and BMI for predicting dyslipidemia, and an unisex cutoff of 0. 5 should be recommended.