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碘海醇与泛影葡胺在CT增强检查160例高危因素的副反应
引用本文:梅红,沈天真,陈星荣. 碘海醇与泛影葡胺在CT增强检查160例高危因素的副反应[J]. 中国新药与临床杂志, 1991, 0(4)
作者姓名:梅红  沈天真  陈星荣
作者单位:上海医科大学附属华山医院放射科,上海医科大学附属华山医院放射科,上海医科大学附属华山医院放射科 上海 200040,上海 200040,上海 200040
摘    要:对有造影剂反应高危因素80例(男44,女36,年龄44±SD 9yr)用非离子型碘海醇100mL(300gI/L)作CT增强检查;另外有造影剂反应高危因素80例(男39,女41,年龄38±SD11yr)用离子型60%泛影葡胺100mL作CT增强检查。结果碘海醇的总副反应、中度反应的发生率均低于泛影葡胺(P<0.01,P<0.05),证明碘海醇在高危因素患者应用的安全性及可靠性。

关 键 词:碘海醇/副作用  泛影葡胺/副作用  造影剂  X线计算机断层摄影术

Adverse reactions of iohexol and diatrizoate meglumine on enhanced CT in 160 high risk factor patients
MEI Hong,SHEN Tian-Zhen,CHEN Xing-Kong. Adverse reactions of iohexol and diatrizoate meglumine on enhanced CT in 160 high risk factor patients[J]. Chinese Journal of New Drugs and Clinical Remedies, 1991, 0(4)
Authors:MEI Hong  SHEN Tian-Zhen  CHEN Xing-Kong
Abstract:The incidences of adverse reactions of non-ionic iohexol and ionic diatri-zoate meglumine (DM) in 160 high risk factor patients undergoing enhanced CT were compared. The dose of iohexol was 100 mL (300 g I/L) in M 44, F 36 (age 44±9 yr), that of DM was 60%, 100 mL in M 39, F 41 (age 38±11 yr) with bolus injection. The incidences of overall and moderate reactions were significantly lower in iohexol group (P<0.0l, P<0.05). The occurrences of heat sensation, nausea, vomiting, urticaria were much less in iohexol group. The results proved the safety and reliability of using iohexol on high risk factor patients.
Keywords:iohexol/adverse effects  diatrizoate meglumiae/adverse effects  contrast media  X-ray computed tomography
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