Multiple Cerebral Infarction Associated with Cerebral Vasculitis in a Patient with Ulcerative Colitis |
| |
| Authors: | Takeshi Yasuda Tomohisa Takagi Daisuke Hasegawa Ryohei Hirose Ken Inoue Osamu Dohi Naohisa Yoshida Kazuhiro Kamada Kazuhiko Uchiyama Takeshi Ishikawa Hideyuki Konishi Yuji Naito Yoshito Itoh |
| |
| Affiliation: | 1.Department of Molecular Gastroenterology and Hepatology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Japan; 2.Department of Gastroenterology and Hepatology, Ayabe City Hospital, Japan |
| |
| Abstract: | A 40-year-old man was admitted to the hospital due to both a worsening of symptoms associated with ulcerative colitis (UC), which had been diagnosed 3 years previously, and limb paralysis. Colonoscopy revealed severe pancolitis-type UC. He was diagnosed with cerebral vasculitis with multiple white matter infarctions associated with the disease activity of UC by contrast-enhanced head magnetic resonance imaging. Mesalazine at 4,000 mg/day and prednisolone at 60 mg/day were started, and the prednisolone dosage was thereafter gradually reduced and switched to golimumab. He achieved a long-term remission from UC, and thereafter his neurological abnormalities improved significantly. He had no recurrence of cerebral infarction. |
| |
| Keywords: | ulcerative colitis cerebral infarction cerebral vasculitis |
|
|
