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Impact of regulatory T cells on the prognosis of hepatocellular carcinoma: A protocol for systematic review and meta analysis
Authors:Xinhui Shi  Qisong Li  Yungang Wang
Affiliation:aDepartment of Medical Laboratory, Yancheng No.1 People''s Hospital & Yancheng First Hospital Affiliated Hospital of Nanjing University Medical School;bCollege of Medical Technology, Jiangsu Vocational College of Medicine, Yancheng, P.R. China.
Abstract:Background:This meta-analysis aimed to systematically review current available literature to assess the impact of regulatory T cells (Tregs) on the prognosis of hepatocellular carcinoma (HCC).Methods:We will browse the online databases of PubMed and Cochrane Library. The summary hazard ratio (HR) and their 95% confidence intervals (CIs) will be combined to present the value reported in the study.Conclusion:Our meta-analysis will provide useful guidance in treatment of HCC based on the reported evidences regarding the impact of Tregs on the prognosis of HCC.OSF registration number:10.17605/OSF.IO/3Q8PW
Keywords:hepatocellular carcinoma   meta-analysis   prognosis   regulatory T cells
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