| 盐酸小檗碱的含量测定方法研究 |
| |
| 引用本文： | 刘征,高延宏. 盐酸小檗碱的含量测定方法研究[J]. 中国伤残医学, 2010, 18(3) |
| |
| 作者姓名： | 刘征 高延宏 |
| |
| 作者单位： | 远达药业集团哈尔滨一洲制药有限公司,黑龙江,哈尔滨,150086;远达药业集团哈尔滨一洲制药有限公司,黑龙江,哈尔滨,150086 |
| |
| 摘 要： | 目的:建立速效止泻胶囊中盐酸小檗碱的含量测定方法。方法:采用高效液相在波长265nm下,以乙腈-0.033mol/L磷酸二氢钾溶液(40:60)为流动相,测定小檗碱的含量。结果:盐酸小檗碱含量测定的线性范围为0.2356～0.8246μg(r=0.9998,n=6),平均加样回收率为99.31%,RSD值为0.89%。结论:方法操作简单,准确可靠,重现性好,可作为速效止泻胶囊中盐酸小檗碱的含量测定方法。
|
| 关 键 词： | 速效止泻胶囊 盐酸小檗碱 质量标准 高效液相色谱法 |
Studies on the Method for the Determination of Berberine Hydrochloride |
| |
| LIU Zheng,GAO Yan-hong. Studies on the Method for the Determination of Berberine Hydrochloride[J]. Chinese JOurnal of Trauma and Disability Medicine, 2010, 18(3) |
| |
| Authors: | LIU Zheng GAO Yan-hong |
| |
| Affiliation: | LIU Zheng,GAO Yan-hong(Heilongjiang Harbin Yat Chau Pharmaceutical Co.Ltd.of Yuanda Pharmaceutical Group,Harbin,Heilongjaing province150086) |
| |
| Abstract: | 0bjective:To establish a method for determination of Berberine Hydrochloride in Suxiaozhixie capsules.Methods:HPLC was used for the determination of Berberine Hydrochloride.The detective wavelength was set at 265nm and the mobile phase was acetonitrile-0.033mol/L potassium dihydrogen phosphate solution(40:60).Results:Berberine Hydrochloride showed a good linearity in the range of 0.2356～0.8246?g(r=0.9998,n=6).The average recovery rate was 99.31%,RSD was 0.89%.Conclution:This method was proved to be simple and accurate with a good reproducibility.It can be used for the determination of Berberine Hydrochloride in Suxiaozhixie capsules. |
| |
| Keywords: | Suxiaozhixie Capsules Berberine hydrochloride Quality Standard HPLC |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
