针刺督脉对脑卒中后认知功能障碍患者事件相关电位的影响

目的：观察针刺督脉对脑卒中认知功能障碍患者事件相关电位的影响,并评价其疗效.方法：将56例脑卒中后认知功能障碍患者随机分为治疗组和对照组各28例.两组患者均予常规药物治疗及康复训练,治疗组加用针刺督脉穴位（百会、神庭穴）治疗.治疗前及治疗后3个月均进行MoCA评分及事件相关电位P300检测.结果：经治疗后,治疗组总有效率为82.1％,对照组总有效率为64.3％,两组比较差异具有统计学意义（ P＜0.05）.两组治疗后MoCA评分均较同组治疗前有明显提高（P＜0.01,P＜0.05）,治疗组治疗后MoCA评分与对照组比较,差异具有统计学意义（P＜0.05）;两组治疗后N2、P3潜伏期较同组治疗前明显缩短（P＜0.01,P＜0.05）,波幅明显增高（P＜0.01,P＜0.05）;治疗组治疗后N2、P3潜伏期及波幅与对照组比较,差异均具有统计学意义（P＜0.05）.结论：针刺督脉可以改善脑卒中后患者的认知功能,事件相关电位可作为卒中后患者认知功能评价的指标.

Effect of Acupuncture Du Meridian on Event-related Potentials in Patients with Cognitive Disorder after Stroke

Objective：To observe the influence of Acupuncture du meridian on P300 of Event-related Potentials in Patients with Cognitive Disorder after stroke. Methods：Fifty-six patients with cognitive disorder after stroke were randomized into a treatment group and a control group, 28 in each. Conventional drugs and Rehabilitation trainings were prescribed to both groups. In addition, the treatment group received Acupuncture du meridian（Baihui and Shenting）. The two groups were compared by evaluating Moca and the P300 before and after the 3-month treatment. Results ： The total effective rate was73.2 % in the treatment group versus82. 1 %, in the control group effective rate was 64.3 %, and the difference was statistically significant （P〈0.05）. The MoCA score had marked improvement in both groups after treatment （P〈0.01, P〈0.05）. After treatment, the MoCA score in the treatment group was significantly better than that in the control group （P〈0.05）. The N2 and P3 latencies were obviously shortened in both groups after treatment （P〈0.01,P〈0.05）, and the amplitude was also significantly increased （P〈0.01,P〈0.05）. After treat ment, N2 and P3 latencies and amplitude in the treatment group were markedly different from that in the control group （P〈0.05）. Conclusion：Acupuncture du meridian can significantly improve the cognitive function of the patients with cognitive disorder after stroke. Event related potential can be used as evaluation index of cognitive function after stroke patients.