新生儿缺氧缺血性脑病脑电图与临床相关性分析

目的分析新生儿缺氧缺血性脑病(HIE)的临床与脑电图(EEG)关系及评估预后。方法对59例临床诊断为HIE的足月新生儿进行自然睡眠脑电图进行回顾分析。结果59例HIE患者中EEG正常21例,异常38例,异常率66.1%。轻度HIE患者脑电图异常率为47.6%,中度HIE患者脑电图异常率为85.7%,重度HIE患者脑电图异常率为100%。结论轻度HIE患者临床治愈较快,中、重度HIE患者特别是EEG爆发抑制,低或平坦背景电压,发作期与发作间期痫样放电预后不良。EEG对HIE患者的诊断及临床随访具有重要价值。

Relativity of EEG and clinical manifestations in hypoxic ischemic encephalopathy of newborn

Objective To analyse the relativity of electroencephalogram (EEG) and clinical manifestations in hypoxic ischemic encephalopathy (HIE) of new born, and evaluate their prognosis. Method The EEG and prognosis results of 59 newborn patients with HIE in natural sleep were analysed retropectively. Results Among the 59 cases there were normal EEGs in 21 cases, abnormal EEGs in 38 cases, thus abormal rate was 66.1%; In the newborn patients with abnormal EEGs, mild HIE was 47.6%, middle HIE was 85.7%, severe HIE was 100%. Conclusion For mild HIE the patients are cured quickly; for middle-severe HIE patients, especialy the patients whom EEG is eraption-suppression, low or smooth background potentials, or epilepsy-like electric discharge at onset or at onset-interval, their prognosis is poor. In a word, EEG has an important value for diagnosing and following-up of the patients with HIH.