枸杞对小鼠辐射损伤后造血系统修复的影响

目的 探讨枸杞在小鼠辐射损伤后造血系统修复过程中的作用。方法 小鼠随机分为3组，正常对照组不做任何处理，喂饲正常饲料；另外2组，给予4.5Gy照射后，喂饲正常饲料或添加枸杞的饲料，1个月后，处死小鼠，应用流式细胞仪分析外周血、脾脏、胸腺及骨髓中各种血细胞。结果 枸杞饲料组小鼠，外周血B细胞增多，骨髓前体B细胞及未成熟B细胞增多，造血干、祖细胞均显著减少。结论 枸杞促进辐射损伤后造血干细胞动员，加速造血系统的恢复。

The Influence of Lycium Chinense Mill on Mice Hematopoietic Reconstruction after Irradiation Injury

Object To investigate the role of Lycium chinense Mill in mice hematopoietic reconstruction after irradiation injury. Method mice were grouped to 3 groups at random, the control group, no treatment with normal food; the other 2 groups, treated with 4.5 Gy irradiation, with normal food or food add Lycium chinense Mill. After 1 month, mice were sacrificed and analyzed the peripheral blood, spleen, thymus and bone marrow cells by flow cytometer. Results Mice feed with Lycium chinense Mill, percentage of B cells increased in the peripheral blood, the pre-B and immature B cells increased too. The percentage of Hematopoietic stem/progenitor cells decreased. Conclusion Lycium chinense Mill can promote the mobilization of Hematopoietic stem/progenitor cells, and accelerate the Hematopoietic reconstruction after irradiation injury.