低聚果糖口服补液盐的试制

目的：改良口服补液盐（ＯＲＳ），使其具有微生态调节作用、并与肠道内渗透压相似。方法：将氯化钠２．６ｇ、氯化钾１．５ｇ、枸橼酸钠２．９ｇ、低聚果糖（ＦＯＳ）２０ｇ和葡萄糖１０ｇ等混合后低聚果糖口服液盐（ＦＯＳ－ＯＲＳ）。密封包装，使用时加开水１０００ｍｌ冲服。可采用高效液相色谱法测定ＦＯＳ的含量。结果：ＦＯＳ－ＯＲＳ为白色散剂，加水后为无色透明液体，味甜中微咸，其浓度（ｍｍｏｌ／Ｌ）为钠７５、钾２０

The preparation of fructooligosaccharide based oral rehydration solution

OBJECTIVE:To optimize the composition of oral rehydration solution(ORS),which had functions of regalating microecosystem,and lower osmolality in intestine.METHODS:Fructooligosaccharide based ORS(FOS ORS) was composed of sodium chloride 2.6g,potassium chloride 1.5g,sodium citrate 2.9g,fructooligosaccharide(FOS) 20g and glucosum 10g.It was sealedin in a package,and dissolved with 1000ml boiled water when administration.It was assayed by high performance liquid chromatography.RESULTS:The form of FOS ORS was a white powder,or a colorless hyaline liquor with water.It tasted sweet with little salty.The concentration(in mol/L) were sodium 75,potassium 20,chloride 65,citric acid 10,FOS 35,glucosum 55,and the total osmolality was 260mmol/L.CONCLUSION:FOS ORS will supply water and electrolyte with lower osmolality,and supply bifidogenic factor that is very effective in the prevention and treatment of dehydration by diarrhea by dysbacteriosis.It is suitable for children patients and can be taken with any antibiotic and other probiotic.