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多发性骨髓瘤药物治疗的新进展
引用本文:刘爱军,陈文明,李利红. 多发性骨髓瘤药物治疗的新进展[J]. 中国癌症杂志, 2006, 16(12): 1083-1087
作者姓名:刘爱军  陈文明  李利红
作者单位:首都医科大学附属北京朝阳医院血液科,北京,100020
摘    要:多发性骨髓瘤(MM)是常见的血液系统肿瘤,但用传统和大剂量化疗仍不能治愈。近年来研制了许多新药或发现了许多药物的新用途,如沙利度胺(thalidomide)及其衍生物、蛋白酶体抑制剂、砷剂等,与传统的MP、VAD方案相比具有更强的缓解率,给我们的临床工作带来巨大帮助。

关 键 词:多发性骨髓瘤  沙利度胺  蛋白酶体抑制剂  砷剂
文章编号:1007-3639(2006)12-1083-05
收稿时间:2006-08-03
修稿时间:2006-10-25

Advance in the medical treatment of multiple myeloma
LIU Ai-jun,CHEN Wen-ming,LI Li-hong. Advance in the medical treatment of multiple myeloma[J]. China Oncology, 2006, 16(12): 1083-1087
Authors:LIU Ai-jun  CHEN Wen-ming  LI Li-hong
Abstract:Multiple myeloma is one of the common hematological malignant disease,but the treatment response was not very promising with conventional and high-dose chemotherapy.There are many new medicines or new therapies having been developed in recent years,such as thalidomide and its derivant,proteasome inhibitors,arsenic trioxide etc,they are more effective than conventional chemotherapy,such as oral melphalan and prednisone(MP);vincristine,doxorubicin,and dexamethasone(VAD).This paper summarize the recent advances in the new options for the treatment of multiple myeloma
Keywords:multiple myeloma   thalidomide   proteasome inhibitors   arsenic agents
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