| 青蒿有效部位及其成分的解热作用研究 |
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| 引用本文： | 李兰芳,郭淑英,张畅斌,杨庆,杜新亮,杨岚,张东,姜廷良.青蒿有效部位及其成分的解热作用研究[J].中国实验方剂学杂志,2009,15(12):65-67. |
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| 作者姓名： | 李兰芳 郭淑英 张畅斌 杨庆 杜新亮 杨岚 张东 姜廷良 |
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| 作者单位： | 中国中医科学院中药研究所,北京,100700 |
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| 摘 要： | 目的:观察青蒿提取物有效部位及其主要成分对大鼠的解热作用。方法:采用鲜酵母致大鼠体温升高的模型,观察青蒿有效部位及其成分对大鼠体温的影响。结果:青蒿中的有效部位(BJQH-A)及主要成分(青蒿乙素、青蒿酸、东茛菪内酯)对鲜酵母致大鼠体温升高具有明显的解热作用。结论:青蒿中含有多个具有解热作用的成分,它们的作用强度、起效时间和作用维持时间各有差别,青蒿的解热作用可能是其活性成分群整合作用的结果。
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| 关 键 词： | 青蒿 解热 青蒿酸 青蒿乙素 东茛菪内酯 |
| 收稿时间： | 2009/7/13 0:00:00 |
Study on the Antipyretic Effect of Active Fraction and Compounds Isolated from Herba Artemisiae Annuae |
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| LI Lan-fang,GUO Shu-ying,ZHANG Chang-bin,YANG Qing,DU Xin-liang,YANG Lan,ZHANG Dong,JIANG Ting-liang.Study on the Antipyretic Effect of Active Fraction and Compounds Isolated from Herba Artemisiae Annuae[J].China Journal of Experimental Traditional Medical Formulae,2009,15(12):65-67. |
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| Authors: | LI Lan-fang GUO Shu-ying ZHANG Chang-bin YANG Qing DU Xin-liang YANG Lan ZHANG Dong JIANG Ting-liang |
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| Institution: | Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences, Beijing 100700,China |
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| Abstract: | Objective:To identify chemical entity of antipyretic action in Herba Artemisiae Annuae.Method: Chemical fractions and compounds from leaves of Herba Artemisiae Annuae.were extracted and isolated systematically and tested on pyretic rats induced by yeast.Those antipyretic effects were determinated and analysed.Results: A fraction and some compounds(arteannuinic acid,artemisinin B,scopoletin) from Herba Artemisiae Annuae.were of antipyretic effect.Conclusion: Antipyretic action of Herba Artemisiae Annuae.depends on the integration effect of its active ingredient group. |
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| Keywords: | Herba Artemisiae Annuae antipyretic arteannuinic acid artemisinin B scopoletin |
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