幽门螺杆菌阴性消化性溃疡出血病因分析

目的探讨幽门螺杆菌（HP）阴性消化性溃疡出血的病因及危险因素。方法选取2010年1月-2012年12月就诊的182例消化性溃疡患者，按出血与否分为两组，出血组85例，无出血组97例。分析HP阴性消化性溃疡出血病因及相关危险因素。结果出血组HP阴性率为41．2％，无出血组HP阴性率为14．4％，两组比较差异有统计学意义（P〈0．05）。结论HP阴性消化性溃疡更易并发消化道出血，与患者年龄、性别、饮酒史、服用非甾体抗炎药等密切相关，应重视HP阴性消化性溃疡患者的治疗。

Etiological Factor Analysis of Peptic Ulcer Hemorrhage with Negative Helicobacter pylori

Objective To discuss the etiological factors and risk factors for peptic ulcer hemorrhage with negative Helicobacterpylori （HP）. Methods A total of 182 patients with peptic ulcer treated in our hospital from January 2010 to December 2012 were chosen in our study. There were 85 cases of hemorrhage among them, with 50 HP positive and 35 HP negative ones. The other 97 patients were without hemorrhage. Etiological factors and correlated risk factors for peptic ulcer hemorrhage with HP negative were analyzed. Results HP negative rate of the hemorrhage group was 41.2%, while that rate of the non-hemorrhage group was 14.4%, and the difference was significant （P 〈 0.05）. The patients with peptic ulcer hemorrhage with negative HP had correlations with age, sex, wine drinking, taking non-steroidal anti-inflammatory medicine and so on. Conclusion Peptic hemorrhage is easily complicated with peptic ulcer with negative HP, and it is intimately correlated with patients＇ age, sex, wine drinking history, and taking non-steroidal anti-inflammatory medicine, etc.