养血清脑颗粒治疗老年高血压患者合并轻度血管性认知障碍的疗效观察

目的：观察养血清脑颗粒对老年高血压合并轻度血管性认知障碍（mVCI）患者认知功能的影响。方法：收集了符合标准的70例患者按就诊顺序随机分为2组,治疗组在基本治疗（如阿司匹林、他汀类、降压等）的基础上给予养血清脑颗粒4.0g,口服,每日3次,连续服药16周,对照组除基本治疗外不使用其他中成药。2组患者治疗前后进行认知功能简易智力状态量表（MMSE）评分。结果：治疗组在治疗后MMSE的总分、主要的几个亚项评分即记忆力、即刻回忆能力、注意力及计算力及收缩压均有明显改善（P〈0.05）。结论：养血清脑颗粒对轻度血管性认知功能障碍患者的记忆力、注意力、理解力有一定的改善作用,且尤其适用于合并有高血压的患者。

The Efficacy of Yangxue Qingnao Granule for Mild Vascular Cognitive Impairment in Senile Patients with Hypertension

Objective：To investigate therapeutic effects of Yangxue Qingnao Granule on cognitive function for senile patients with mild vascular cognitive impairment and hypertension. Methods：Seventy cases were randomly divided into treatment group （Yangxue Qingnao Granule plus basic treatment, in a regimen 4.0g tid for 16 weeks） and control group （ basic treatment only）. Score all patients according to MMSE systems before and after treatment. Results： Compared with the control group, the treatment group responded well to the granule in terms of memory, attention and calculation function （ P 〈 0.05 ）, and decreased significantly as for level of systolic blood pressure. Conclusion ：Yangxue Qingnao Granule significantly improved memory, attention and calculation function for patients with mild vascular cognitive impairment accompanied by hypertension.