| 格拉司琼治疗53例顺铂所致呕吐临床观察 |
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| 引用本文： | 朱红成,张雪鹏,赵光明,李瑞伟,张文杰. 格拉司琼治疗53例顺铂所致呕吐临床观察[J]. 肿瘤学杂志, 2004, 10(1): 43-44 |
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| 作者姓名： | 朱红成 张雪鹏 赵光明 李瑞伟 张文杰 |
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| 作者单位： | 华北煤炭医学院附属医院,河北,唐山,063000 |
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| 摘 要： | [目的]观察格拉司琼对顺铂所致恶心、呕吐的临床疗效.[方法]53例接受含顺铂联合化疗的恶性肿瘤患者进行2个疗程的自身对照,随机分格拉司琼与胃复安组,比较治疗效果.[结果]格拉司琼组对恶心、呕吐的完全控制率和有效控制率明显优于胃复安组(P＜0.05).两组间不良反应发生率无明显差异.[结论]格拉司琼可作为预防化疗引起的恶心、呕吐的优选药物.
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| 关 键 词： | 格拉司琼 药物疗法 副反应 呕吐 |
| 文章编号： | 1671-170X(2004)01-0043-02 |
| 修稿时间： | 2003-11-12 |
Clinical Study of Granisetron for Cisplatin Induced Vomiting in 53 Cases |
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| ZHU Hong-cheng,ZHANG Xue -peng,ZHAO Guang - ming,et al.. Clinical Study of Granisetron for Cisplatin Induced Vomiting in 53 Cases[J]. Journal of Chinese Oncology, 2004, 10(1): 43-44 |
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| Authors: | ZHU Hong-cheng ZHANG Xue -peng ZHAO Guang - ming et al. |
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| Abstract: | To investigate efficacy of granisetron for cisplatinum induced nausea and vomiting.Fifty-three cases with malignancy receiving2courses of cisplatin based combination chemotherapy were random-ized into2groups(with granisetron or maxolon).The antiemetic efficacy was compared between the2groups.Granisetron was supetrior to metoclopramide in the prevention of nausea and vomiting with significant dif-ference(P<0.05).The rate of toxicity occurred in2group was not significantly different.[Conclusion]Granisetron is a good choice drug in the prevention of chemotherapy induced nausea and vomiting. |
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| Keywords: | granisetron drug therapy side effect vomit |
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