| 速效抗晕胶囊质量标准研究 |
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| 引用本文： | 张术,储智勇,娄子洋,栾洁,沈越,董昕. 速效抗晕胶囊质量标准研究[J]. 解放军药学学报, 2011, 27(1): 40-43. DOI: 10.3969/j.issn.1008-9926.2011.01.012 |
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| 作者姓名： | 张术 储智勇 娄子洋 栾洁 沈越 董昕 |
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| 作者单位： | 1. 海军医学研究所,上海,200433
2. 第二军医大学药学院,上海,200433 |
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| 基金项目： | 海军医学研究所基金项目,No.06A202 |
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| 摘 要： | 目的 确定速效抗晕胶囊的质量检测标准.方法 采用薄层色谱法定性鉴别干姜提取物,用高效液相色谱法测定硫酸右旋苯丙胺和茶苯海明含量.结果 薄层色谱法鉴别专属性强;高效液相色谱法中,硫酸右旋苯丙胺在244～366μg/ml范围内浓度与吸收度呈良好线性关系(r=0.9999),平均回收率为99.54%,RSD为0.81%;茶苯...
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| 关 键 词： | 速效抗晕胶囊 质量标准 薄层色谱法 高效液相色谱法 硫酸右旋苯丙胺 茶苯海明 |
Studies on Quality Standards of Suxiaokangyun Capsules |
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| ZHANG Shu,CHU Zhi-yong,LOU Zi-yang,LUAN Jie,SHEN Yue,DONG Xin. Studies on Quality Standards of Suxiaokangyun Capsules[J]. Pharmaceutical Journal of Chinese People's Liberation Army, 2011, 27(1): 40-43. DOI: 10.3969/j.issn.1008-9926.2011.01.012 |
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| Authors: | ZHANG Shu CHU Zhi-yong LOU Zi-yang LUAN Jie SHEN Yue DONG Xin |
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| Affiliation: | ②①Naval Medical Research Institute of PLA,Shanghai 200433,China;②Second Military Medical University,Shanghai 200433,China |
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| Abstract: | Objective To establish quality specifications for Suxiaokangyun Capsules.Methods Zingiber was identified by thin layer chromatography.The content of D-amphetamine sulfate and dimentydrinate was determined by high performance liquid chromatography.Results Zingiber could by specifically identified by thin layer chromatography.The amount of inlet D-amphetamine sulfate had a good linearity with the response value of the peak area in the range of 244-366 μg/ml（r=0.9999）.The average recovery of D-amphetamine sulfate was 99.54%,RSD was 0.81%.For dimentydrinate,the range was of 0.32-0.48 mg/ml（r=0.9999）,and the average recovery was 99.56% while RSD was 1.06%.Conclusion The method is reliable,simple,reproducible,and can be used for the quality control of Suxiaokangyun Capsules. |
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| Keywords: | Suxiaokangyun Capsules quality standard thin layer chromatography high performance liquid chromatography D-amphetamine sulfate dimentydrinate |
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