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中草药及药用植物治疗绝经后骨质疏松症——从基础研究到临床评价
引用本文:许英,王小云.中草药及药用植物治疗绝经后骨质疏松症——从基础研究到临床评价[J].辽宁中医杂志,2009(10):1647-1651.
作者姓名:许英  王小云
作者单位:广州中医药大学;广东省中医院;
摘    要:绝经后骨质疏松症(postmenopausal osteoporosis,PMOP)是一种严重威胁绝经后妇女健康的全身性骨病。目前PMOP常用药物治疗,包括激素补充治疗(HRT)等,由于乳腺癌或心血管疾病等风险在一定程度上限制了其临床应用。国内外进行的基础研究和临床试验结果显示,一些中草药(Chinese Herbal Medicine)(包括淫羊藿、葛根、丹参、骨碎补、接骨木、蛇床子、山茱萸、菟丝子、女贞子及仙茅等)及药用植物(medicinal plants)(包括大豆异黄酮、总状升麻、红花子、黑榆及黄蜀葵花等)提取物及(或)生物活性成分具有抗PMOP的作用。对该类药物及化合物的基础研究及临床试验结果进行综述。

关 键 词:绝经后骨质疏松症  中草药  药用植物  治疗

Treatment for Postmenopausal Osteoporosis with Chinese Herbal Medicine and Medicinal Plant:from Experimental Study to Clinical Evaluation
XU Ying,WANG Xiao-yun.Treatment for Postmenopausal Osteoporosis with Chinese Herbal Medicine and Medicinal Plant:from Experimental Study to Clinical Evaluation[J].Liaoning Journal of Traditional Chinese Medicine,2009(10):1647-1651.
Authors:XU Ying  WANG Xiao-yun
Institution:1.Postgraduate for MD;Guangzhou University of Chinese Medicine;Guangzhou 510405;Guangdong;China;2.Department of Gynecology;Guangdong Provincial Hospital of Traditional Chinese Medicine;Guangzhou 510120;China
Abstract:Postmenopausal osteoporosis(PMOP)is one of serious systemic bone diseases to harm the health of postmenopausal women.The common pharmacotherapies for PMOP,including hormone replacement therapy(HRT),have been restricted in clinical application for the potential risk of breast cancer and cardiovascular diseases.The results of several experimental studies and clinical trials indicated that some Chinese Herbs(including Herba Epimedii,Radix Puerariae Lobatae,Radix Salviae Miltiorrhizae,Rhizoma Drynariae,Sambucus...
Keywords:postmenopausal osteoporosis(PMOP)  Chinese herbal medicine  medicinal p/ants  treatment
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