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正交试验法优选补阳还五汤水煎煮工艺
引用本文:王弋然,张星,毛春芹,陆兔林.正交试验法优选补阳还五汤水煎煮工艺[J].中国实验方剂学杂志,2012,18(23):25-28.
作者姓名:王弋然  张星  毛春芹  陆兔林
作者单位:1. 南京市中医院,南京,210001
2. 南京中医药大学药学院,南京,210046
基金项目:国家中医药行业科研专项(201007010)
摘    要:目的:优选补阳还五汤的水煎煮工艺。方法:以黄芪甲苷、阿魏酸含量为指标,选取浸泡时间、煎煮时间、煎煮次数、加水量及浓缩量为考察因素,采用正交试验法优选补阳还五汤的水煎煮工艺。结果:最佳水煎煮工艺为浸泡30 min,加10倍量水煎煮2次,每次30 min。结论:优选的水煎煮工艺稳定可行,可应用于补阳还五汤的大生产。

关 键 词:补阳还五汤  黄芪甲苷  阿魏酸  水煎煮工艺  正交试验
收稿时间:7/4/2012 12:00:00 AM

Optimization of Water Boiling Technology of Buyang Huanwu Decoction by Orthogonal Test
WANG Yi-ran,ZHANG Xing,MAO Chun-qin and LU Tu-lin.Optimization of Water Boiling Technology of Buyang Huanwu Decoction by Orthogonal Test[J].China Journal of Experimental Traditional Medical Formulae,2012,18(23):25-28.
Authors:WANG Yi-ran  ZHANG Xing  MAO Chun-qin and LU Tu-lin
Institution:Nanjing Hospital of Traditional Chinese Medicine,Nanjing 210001,China;College of Pharmacy,Nanjing University of Chinese Medicine, Nanjing 210046,China;College of Pharmacy,Nanjing University of Chinese Medicine, Nanjing 210046,China;College of Pharmacy,Nanjing University of Chinese Medicine, Nanjing 210046,China
Abstract:Objective: To optimize water boiling process of Buyang Huanwu decoction. Method: With the content of astragaloside and ferulic acid as indexes,orthogonal test was used to optimized water boiling technology of Buyang Huanwu decoction with soaking time,boiling time,boiling times and concentrated volume as factors. Result: The best water decoction technology was:soaked 30 min with 10 folds water,boiled 2 times with 30 min per time. Conclusion: Optimzed technology was reasonable,feasible and reproducible,it could be applied in mass production of Buyang Huanwu decoction.
Keywords:Buyang Huanwu decoction  astragaloside  ferulic acid  water boiling process  orthogonal test
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