超敏C反应蛋白水平在妊娠期糖尿病发展过程中的意义

目的:考察超敏C反应蛋白水平在妊娠期妇女糖尿病发展过程中的意义。方法:收集2010年3月～2011年9月妊娠期妇女87例,分为正常糖耐量孕妇组35例、妊娠期糖耐量受损孕妇组32例及妊娠糖尿病孕妇组20例,测定各组血清超敏C反应蛋白水平,并将同期体检健康的女性39例作为对照。结果:与健康对照组相比,正常妊娠组的空腹血糖和超敏C反应蛋白差异无统计意义(P>0.05);与正常妊娠组相比,糖耐量受损孕妇组和糖尿病孕妇组的空腹血糖和超敏C反应蛋白明显增高(P<0.05);与糖耐量受损孕妇组相比,糖尿病孕妇组的空腹血糖和超敏C反应蛋白水平更高(P<0.05)。结论:超敏C反应蛋白升高可预测妊娠糖期尿病发生。

Significance of high-sensitive C-reactive protein level in the course of development of gestational diabetes mellitus

Objective:To explore the significance of high-sensitive C-reactive protein(hs-CRP) level in the course of development of gestational diabetes mellitus(GDM).Methods:Eighty-seven pregnant women were selected from March 2010 to September 2011,then they were divided into normal glucose tolerance group(35 cases),gestational impaired glucose tolerance group(32 cases),and GDM group(20 cases);the levels of serum hs-CRP in different groups were detected,39 healthy women who received physical examination during the same period were selected as control group.Results:There was no significant difference in the fasting blood glucose and hs-CRP level between health control group and normal pregnancy group(P>0.05).The fasting blood glucose and hs-CRP level in gestational impaired glucose tolerance group and GDM group were significantly higher than those in normal pregnancy group(P<0.05).The fasting blood glucose and hs-CRP level in GDM group were significantly higher than those in gestational impaired glucose tolerance group(P<0.05).Conclusion:The increase of hs-CRP level can predict the occurrence of GDM.