右美托咪定对高血压患者全身麻醉拔管期心率收缩压乘积和血压心率比值的影响

目的:观察右美托咪定对高血压患者全身麻醉拔管期心率收缩压乘积(RP P)和血压心率比值(PRQ)的影响.方法:选择97例需行全麻手术且合并有高血压的患者作为研究对象,所有患者均给予常规麻醉,随机将其分为两组,观察组(n=49)在术前30min静脉注射0.5μg/kg右美托咪定,对照组(n=48)在相同时刻静脉注射等量生理盐水,对比两组患者给药前(T0)、拔管前(T1)、拔管时(T2)、拔管后5min(T3)、拔管后10min(T4)的HR、SBP、DBP、MAP等指标,计算RPP和PRQ差异情况.结果:观察组T1、T2时的HR显著低于对照组(P均<0.05),T1、T2、T3的SBP、DBP、MAP显著低于对照组(P均<0.05);观察组的T1～T4的RPP显著低于对照组(P均<0.05),但两组T0～T4的PRQ比较差异无统计学意义(P均>0.05);两组患者在研究时间均未见严重不良反应.结论:右美托咪定可以有效降低高血压患者全身麻醉拔管期的RP P,保证更好的血流动力学指标稳定性和更低的心血管反应,提高拔管质量.

Beauty's Microphones Set Right Decannulation Period of General Anesthesia in Patients with High Blood Pressure Heart Rate,Systolic Blood Pressure Product ( RPP) Ratio ( PRQ) the Influence of Heart Rate and Blood Pressure

Objective:To observe the tora microphones set decannulation period of general anesthesia in patients with high blood pressure heart rate, systolic blood pressure product (RPP) ratio (PRQ) the effects of heart rate and blood pressure.Method:Choose 97 cases of general anesthesia, surgery combined with hyper-tension patients as the research object, all the patients were given general anesthesia, it can be divided into two groups at random, the observation group ( n = 49) in preoperative 30 min intravenous 0.5 mu g/kg right beautiful mi set, the control group ( n = 48) intravenous injection amount of normal saline in the same time, compared two groups of patients with medication ( T0 ) , tube drawing before ( T1 ) , when the tube drawing ( T2) , 5 min after extubation ( T3) , 10 min after extubation ( T4) HR, SBP , DBP , MAP and other indica-tors, calculate the RPP and PRQ differences.Results:Observation group T1, T2 of HR was significantly lower than control group (P <0.05), T1, T2, T3, SBP, DBP, MAP was significantly lower than the control group (P < 0.05);Observation group of T1 ～ T4 RPP was significantly lower than the control group (P < 0.05), but the T0 ～ T4 PRQ was similar between the two groups had no statistical significance (P > 0.05);Two groups of patients in the study were no serious adverse reaction.Conclusion:Right beautiful mi set which can effectively reduce the high blood pressure patients decannulation period of general anesthesia RPP, guarantee better stability and lower cardiovascular hemodynamic parameters reaction, improve the quality of tube draw-ing.