参芪扶正注射液联合化疗治疗肺癌的临床观察 |
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引用本文: | 李青山,白璐,高东奇,张晶晶,连相尧,胡潺潺,张振军. 参芪扶正注射液联合化疗治疗肺癌的临床观察[J]. 河北医学, 2017, 23(9). DOI: 10.3969/j.issn.1006-6233.2017.09.025 |
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作者姓名: | 李青山 白璐 高东奇 张晶晶 连相尧 胡潺潺 张振军 |
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作者单位: | 承德医学院附属医院肿瘤科,河北 承德,067000 |
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基金项目: | 2015年河北省承德市科学技术研究与发展计划项目 |
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摘 要: | 目的:探讨参芪扶正注射液肺癌化疗患者近期疗效及免疫功能的影响.方法:将74例放疗肺癌患者,随机分为试验组(参芪扶正组)、阳性对照组(艾迪注射液组)及空白对照组.结果:试验组总有效率优于空白对照组,差异有统计学意义(P<0.05).治疗后,试验组在CD3+、CD4+、CD4+/CD8+及NK细胞与阳性对照组无差异(P>0.05),而空白对照组治疗后CD3+、CD4+、CD8+、CD4+/CD8+比值均低于治疗前(P<0.05),且治疗后试验组的CD3+、CD4+、CD4+/CD8+比值与空白对照组比较差异有统计学意义(P<0.05).结论:参芪扶正注射液能改善肺癌患者的免疫功能,提高化疗疗效.
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关 键 词: | 参芪扶正注射液 肺癌 化疗 免疫功能 |
Clinical Observation with Lung Cancer Undergoing Shenqifuzheng Combined Themotherapy |
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Abstract: | Objective:To investigate the effects of Shenqifuzheng Injection on quality of life and immune function in patients with chemotherapy of lung cancer. Methods:We analyzed 74 cases of lung cancer patients randomly divided into treatment group ( Shen Qi Fu Zheng group ) , positive control group ( Addie injection group) and blank control group. Results:In terms of total effective rate, the treatment group was higher than the blank group, the difference was significant ( P < 0.05) . After treatment, the CD3+, CD4+, CD4+/CD8+and NK cells were no difference between the treatment group and the control group ( P>0.05) , While the con-trol group after treatment, CD3, CD4+, CD8+, CD4+/CD8+ ratio were lower than before treatment ( P<0.05 or P<0.01).After treatment, the CD3+, CD4+, CD4+/CD8+ ratio and the blank control group had statistical significance with the treatment group (P<0.05).Conclusion:Shen Qi Fu Zheng Injection combined with che-motherap can improve the curative effect and the immune function in the lung cancer patients. |
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Keywords: | Shen Qi Fu Zheng Lung cancer Chemotherapy Immune function |
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