丙酸氟替卡松明胶海绵在鼻内镜鼻窦术后术腔应用的疗效观察

目的:观察丙酸氟替卡松明胶海绵对慢性鼻窦炎患者在功能性鼻内镜鼻窦术后换药中的临床应用疗效.方法:选择120例行双侧鼻窦内镜手术且完成随访的CRSwNP和CRSsNP患者为研究对象.分为实验组(左侧鼻腔)和对照组(右侧鼻腔),实验组在术后第二天抽完中鼻道填塞材料后用丙酸氟替卡松浸润的明胶海绵填塞术腔,术后2周、2月、4月换药方法同上,对照组用0.9%生理盐水浸润的明胶海绵填塞术腔,术后2周,2月,4月换药方法同上,以视觉模拟评分法(VAS)主观评估及Lund-Kennedy客观评估为标准观察术后2周、2月、4月的疗效.结果:术后2周、2月、4月三个时间,两组组间对照差异有统计学意义(P<0.05).结论:应用丙酸氟替卡松浸润的明胶海绵填塞术腔在此类手术后换药,具有良好的消炎、减轻黏膜水肿、减少囊肿生成的作用,可以促进术腔尽早恢复.

Efficacy of Fluticasone Propionate Gelatin Sponge in Postoperative Endoscopic Sinus Surgery

Objective:To observe the clinical efficacy of fluticasone propionate gelatin sponge in chronic sinusitis patients after functional endoscopic sinus surgery. Methods: 120 patients underwent bilateral endo-scopic sinus surgery and CRSwNP and CRSsNP patients were followed up for the study. They were divided into experimental group ( the left nasal cavity) and the control group ( the right side of the nasal cavity) . In the ex-perimental group, the nasal passages were filled second days after operation and the gelatin sponge filled with fluticasone propionate was used to fill the cavity. After 2 weeks, February and April, the dressing change was the same as before. By using visual analogue scale ( VAS) and subjective assessment LundKennedy objective assess the efficacy of the 2 week of February, and April as the standard observation after operation. Results:The difference between the two groups was statistically significant at 2 weeks, three weeks, February and April ( P < 0.05) . Conclusion:The application of gelatin sponge filled with fluticasone propionate in the dressing cavity has good anti-inflammatory, mucosal edema and reduced cyst formation. It can promote the recovery of the cavity as soon as possible.