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| 模拟测定103Pd放射性支架在血管中的剂量分布 | |
| 引用本文： | 苑淑渝,戴光复,徐志勇,孙福印,许书河,马凤武.模拟测定103Pd放射性支架在血管中的剂量分布[J].中华核医学杂志,2003,23(2):104-106. |
| 作者姓名： | 苑淑渝 戴光复 徐志勇 孙福印 许书河 马凤武 |
| 作者单位： | 1. 300192,天津,中国医学科学院、中国协和医科大学放射医学研究所 2. 中国原子能科学研究院 3. 天津市卫生防病中心 |
| 基金项目： | 国家自然科学基金资助项目 (30 1 70 2 33) |
| 摘 要： | 目的 测定血管内^103Pd放射性支架的剂量分布。方法 采用肌肉组织等效材料代替血管壁，用热释光剂量计模拟测量血管内的剂量分布。结果 当支架活度为9．8MBq时，支架表面累积吸收剂量为9．8Gy(17d)。^103Pd支架表面的剂量分布随径向距离增加而迅速减少，在支架表面径向距离0．4mm处80％的剂量被血管壁吸收。结论 血管内^103Pd支架对血管周围的器官和组织无明显损害。 |
| 关 键 词： | 冠脉再狭窄 模拟测定 ^103Pd放射性支架 血管 剂量分布 |
| 修稿时间： | 2002年4月28日 |
Simulative study on dose distribution of 103Pd stent in blood-vessel |
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| YUAN Shu yu,DAI Guang fu,XU Zhi yong,et al..Simulative study on dose distribution of 103Pd stent in blood-vessel[J].Chinese Journal of Nuclear Medicine,2003,23(2):104-106. | |
| Authors: | YUAN Shu yu DAI Guang fu XU Zhi yong |
| Institution: | YUAN Shu yu,DAI Guang fu,XU Zhi yong,et al. Institute of Radiation Medicine,CAMS and PUMC,Tianjin 300192,China |
| Abstract: | Objective To evaluate the dose distribution of 103 Pd stent in the blood vessel. Methods Simulative study on dose distribution of endovascular 103 Pd stent was conducted with thermoluminescence dosimeter. The vessel wall was substituted by muscle equivalent material in this simulative study. Results When radioactivity of the study 103 Pd stent was 9.8 MBq the absorbed dose from the stent surface by muscle equivalent material was 9.8 Gy at 17 d (the half life period of 103 Pd). The radioactivity of 103 Pd stent surface rapidly attenuated over the radial distance. 80% of the radioactivity at the area that was radially 0.4 mm apart from the stent surface was absorbed by the simulative blood vessel wall. Conclusion Endovascular 103 Pd stent does not exert significant injury on the surrounding organs or tissues. |
| Keywords: | Blood vessels Brachytherapy Radiation dosage Models structural Stents Pd$$$$ |
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