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蜘蛛香中1个新的单萜环烯醚酯类化合物
引用本文:王伟倩,周东恒,朱英,程汝滨,杨波.蜘蛛香中1个新的单萜环烯醚酯类化合物[J].中草药,2016,47(22):3944-3946.
作者姓名:王伟倩  周东恒  朱英  程汝滨  杨波
作者单位:浙江中医药大学药学院, 浙江 杭州 310053;浙江中医药大学药学院, 浙江 杭州 310053;浙江中医药大学药学院, 浙江 杭州 310053;浙江中医药大学药学院, 浙江 杭州 310053;浙江中医药大学药学院, 浙江 杭州 310053
基金项目:浙江省医药卫生科技计划(2014KYA152);浙江省公益性技术应用研究计划(2014C33215);浙江省中医药科技计划(2016ZA050);重中之重一级学科建设2013、2014年配套经费-中药学(开放基金-杨波)
摘    要:目的研究败酱科缬草属植物蜘蛛香Valeriana jatamansi根及根茎的化学成分。方法采用硅胶柱色谱、中压色谱、制备型HPLC等方法进行分离、纯化,采用1D,2D NMR、HRMS、IR等波谱学方法鉴定化合物化学结构。结果从蜘蛛香二氯甲烷提取物中分离、纯化得到1个新的单萜环烯醚酯类成分,命名为蜘蛛香萜C(1)。结论化合物1为新的单萜环烯醚酯类成分。

关 键 词:败酱科  缬草属  蜘蛛香  单萜环烯醚酯  蜘蛛香萜C
收稿时间:2016/5/31 0:00:00

A novel iridoid ester from roots and rhizomes of Valeriana jatamansi
WANG Wei-qian,ZHOU Dong-heng,ZHU Ying,CHENG Ru-bin and YANG Bo.A novel iridoid ester from roots and rhizomes of Valeriana jatamansi[J].Chinese Traditional and Herbal Drugs,2016,47(22):3944-3946.
Authors:WANG Wei-qian  ZHOU Dong-heng  ZHU Ying  CHENG Ru-bin and YANG Bo
Institution:College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China;College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China;College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China;College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China;College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 310053, China
Abstract:Objective To study the chemical constituents from the roots and rhizomes of Valeriana jatamansi in Valeriana Linn., Valerianaceae. Methods The chemical constituents were separated and purified by silica gel, medium pressure column chromatography, and preparative HPLC. Their structures were determined by 1D, 2D NMR, HRMS, and IR spectroscopic analyse. Results An iridoid ester was isolated from the dichloromethane extract from the roots and rhizomes of V. jatamansi, which was named as valerjatadoid C. Conclusion Compound 1 is a new iridoid ester.
Keywords:Valerianaceae  Valeriana Linn    roots and rhizomes of Valeriana jatamansi  iridoid ester  valerjatadoid C
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