Plasma exchange in refractory cutaneous vasculitis |
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Authors: | A.N. TURNER S. WHITTAKER I. BANKS R.RUSSELL JONES C.D. PUSEY |
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Affiliation: | Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K. |
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Abstract: | Eight patients with intractable cutaneous leucocytoclastic vasculitis were given a trial of plasma-exchange therapy. All but one improved, five substantially. Four have been successfully treated by intermittent plasma exchange for periods of 5-12 years. Apart from one episode of hepatitis B, possibly related to administration of fresh frozen plasma, no major adverse effects have occurred. Plasma exchange can be a valuable therapeutic option in patients with severe refractory cutaneous vasculitis. |
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