体重指数和血清甘油三酯水平对急性胰腺炎预后的影响研究

目的研究体重指数和血清甘油三酯水平对急性胰腺炎预后的影响,为临床防治急性胰腺炎提供一定的理论依据。方法临床入选183例急性胰腺炎患者,根据病情严重程度分为轻型组（92例）与重型组（91例）,统计分析两组患者的相关临床资料。结果在体重正常患者中MAP的发生率为47.83%,而SAP发生率为27.47%,两者具有统计学差异（P〈0.05）;在体重超重者患者中MAP和SAP发生率分别为39.13%、43.00%,两组间没有统计学差异（P〉0.05）;在肥胖患者中SAP发生率（28.57%）明显高于MAP发生率（13.04%）（P〈0.05）。与TG水平正常组相比较,高脂血症组的血钙和PaO2水平明显降低（P〈0.05）,同时高脂血症组的血清肌酐和血糖水平也是显著升高的（P〈0.05）。同时,两组患者在血清甘油三酯水平和体重指数方面均具有统计学差异（P〈0.05）。结论血清甘油三酯水平和体重指数可能是预测急性胰腺炎病情严重程度的两个危险因素。

Effect of body mass index and serum triglyceride level on prognosis of acute pancreatitis

Objective To investigate the effect of body mass index and serum triglyceride level on prognosis of acute pancreatitis and to provide theoretical references for the prevention and treatment in clinics.Methods One hundred and eighty-three patients with acute pancreatitis were retrospectively reviewed and randomly divided into mild acute pancreatitis group（MAP group,n=92） and severe acute pancreatitis group（SAP group,n=91）.Results For patients with normal weight,the incidence of MAP was 47.83% and that of SAP was 27.47%,there were significant differences between the two groups（P0.05）.For overweighed patients,the incidences of MAP was 39.13% and that of SAP was 43.00%,there was no significant difference between the two groups（P0.05）.The incidence of SAP was significantly higher than that of MAP in patients with obesity,28.57%vs.13.04%（P 0.05）.The levels of calcium and PaO2 in hyperlipidemia group were decreased compared with those in normal triglyceride group（P0.05）,meanwhile the Scr and blood sugar levels of hyperlipidemia group were also significantly elevated（P0.05）.Significant differences in serum triglyceride levels and body mass index were observed between the two groups（P0.05）.Conclusion The serum triglyceride levels and body mass index may be the risk factors predicting the severity of acute pancreatitis.