早期喂养降低新生儿高胆红素血症发生率的临床研究

目的探讨早期喂养与新生儿高胆红素血症发生率的关系。方法 120例足月健康新生儿随机分为观察组和对照组各60例,观察组采取混合喂养的方式达到早期足量喂养,对照组单纯母乳喂养,比较两组新生儿胎粪排出时间、大便转黄时间、高胆红素血症发生率以及胆红素水平,并观察产妇首次泌乳时间。结果观察组在胎粪排出时间、大便转黄时间上均较对照组短,高胆红素血症发生率低于对照组,差异均有统计学意义（均P〈0.05）;产妇泌乳时间差异无统计学意义（P〉0.05）。结论早期喂养尽早达到足量喂养能降低新生儿高胆红素血症发生率和严重程度,并不影响产妇泌乳。

The clinical effect of early feeding in reducing the incidence of neonatal bilirubin hematic disease

Objective To understand the effect of early feeding in reducing the incidence rate of hyperbilirubinemia in neonates. Methods 120 cases of full-term newborns in the hospital were randomly divided into an experimental group and a control group,with 60 cases in each group. The experimental group was administered with mixed feeding to achieve early full feeding whereas the control group was administered with breast feeding only. The neonates in the two groups were compared in the aspects of meconium discharge time,stool turning yellow,the incidence of hyperbilirubinemia and bilirubin level,and observed maternal first lactation time. Findings In the observation group,the meconium discharge time and fecal yellowing time were shorter than that of the control group. The incidence of hyperbilirubinemia and bilirubin levels were lower than in the control group. The differences were significant（ P〉 0. 05）; No significant difference was found in maternal lactation time（ P〈 0. 05）. Conclusion Early and adequate feeding can reduce the incidence and severity of neonatal hyperbilirubinemia. However,it was found to bear insignificant effect on lactation.