A case of postoperative gastric cancer responding to adjuvant chemotherapy with TS-1--a novel oral formation of 5-fluorouracil] |
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Authors: | T Yamada M Morishita K Yoshida S Kinoshita K Yokoi M Nakamura K Morita T Harada S Yagi S Kitagawa M Nakagawa |
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Affiliation: | Dept. of Surgery, Ishikawa Prefectural Central Hospital. |
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Abstract: | TS-1 is a novel oral formation of 5-fluorouracil, developed using tegafur and two biochemical modulations. We report the case of a patient with multiple lymph node metastases from gastric cancer that markedly responded to TS-1. A 70-year-old man suffering from hematemesis was admitted to our hospital. Computed tomography showed advanced gastric cancer with huge lymph node metastases. After non-curative operation, he received adjuvant chemotherapy with TS-1 for 12 weeks. CT revealed that almost complete reduction of the metastatic nodes was obtained. No serious adverse reactions were observed. |
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