乙型肝炎患者血清单胺氧化酶的检测

目的:探讨乙肝患者血清单胺氧化酶水平及其临床意义。方法:用快速比色法检测急性乙肝、慢性乙肝、重型乙肝、肝硬化患者血清MAO水平。结果:乙肝患者血清MAO为(46.68±20.64)u,而正常对照组MAO为(23.25±12.40)u,差异具显著性(P<0.01),且慢性乙肝、重型乙肝、肝硬化血清MAO值均高于正常对照组。急性、慢性、重型乙肝、肝硬化患者血清MAO阳性率依次为45%、50%、65%、82.5%,差异显著(P<0.01)。结论:MAO与肝纤维化密切相关,是反映肝纤维化程度及肝损害的重要指标。

Detection of monoamine oxidase in sera of patient with hepatitis B

Objective To detect the level of monoamine oxidase(MAO)in sere of patients with hepatitis B and its clinical significance.Methods MAO in 160 subjects with hepatitis B was measured with tachycolorimetry,and the value of more than 40u was judged to be positive.Results The levels of MAO in patients and nomal control,were(46.68±20.64)u and(23.2±12.40)u,respectively Statistics,found significant,difference between them(p<0.01).And the levels of MAO in cases with chronic hepatitis,severe hepatits and cirrhosis,higher than those in normal control group(p<0.01).The positive rotes of MAO in cases with acute hepatitis,chronic hepatitis,severe hepatitis and cirrhosis were 45%, 50%,65% and 82.5%,respectively(p<0.01).Conclusion The activities of MAO in hepatitis B are related to hepatic cirrhosis.