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以存活素为靶点的反义寡核苷酸在胰腺癌治疗中的研究
引用本文:刘海威,刘志明. 以存活素为靶点的反义寡核苷酸在胰腺癌治疗中的研究[J]. 医学综述, 2008, 14(20): 3084-3086
作者姓名:刘海威  刘志明
作者单位:广西医科大学第一附属医院胃肠外科,南宁,530021
摘    要:反义寡核苷酸具有高特异性、靶向性、无毒性等特有的优点,近年来一直是抗肿瘤、抗病毒领域研究的热点。为恶性肿瘤的治疗提供了一种新方法。本文就以survivin为靶点的反义寡核苷酸的作用机制及与胰腺癌关系进行综述。

关 键 词:存活素  反义  寡核苷酸  胰腺癌

Study Progress of Survivin Antisense Oligonucleotides in Therapy of Pancreatic Cancer
LIU Hai-wei,LIU Zhi-ming. Study Progress of Survivin Antisense Oligonucleotides in Therapy of Pancreatic Cancer[J]. Medical Recapitulate, 2008, 14(20): 3084-3086
Authors:LIU Hai-wei  LIU Zhi-ming
Affiliation:LIU Hai-wei,LIU Zhi-ming.(Department of Gastrointestinal Surgery,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China)
Abstract:Survivin Antisense Oligonucleotides has the advantages of high specificity,targeting effect and non toxic and so on. It is also the Hot Research of anti-tumor and anti-virus. At the same time, it provide a new way for the therapy of malignant tumors. This article reviews progress about the mechanism of Survivin Antisense Oligonucleotides and the relation with the Pancreatic Cancer.
Keywords:Survivin  Antisense  Oligonucleotides  Pancreatic cancer  
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