隐孢子虫病实验与临床研究——Ⅲ.实验小鼠隐孢子虫病透射电镜观察

描述对免疫抑制小鼠肠上皮细胞寄生的隐孢子虫滋养体、裂殖体和大配子的超微结构及肠上皮细胞改变的透射电镜观察结果。虫体在肠上皮细胞附着处可见一明显电子致密带,并被肠上皮细胞来源的纳虫空泡包围。虫体在附着处其胞浆膜形成复杂的膜性皱褶并和肠上皮细胞质膜紧密接触。在裂殖子内可见电子致密颗粒和棒状体样结构,其意义尚不明瞭。

EXPERIMENTAL AND CLINICAL STUDY ON CRYPTOSPORIDIASIS III. ULTRASTRUCTURAL OBSERVATION ON CRYPTOSPORIDIUM IN IMMUNOSUPPRESSED MICE

The ultrastructure of Cryptosporidium parvum, which parasitized on the surface of the intestine of the immunosuppressed mice,was studied by transmission electron microscopy. The parasite was enveloped by the parasitophorous vacuole developed from the host epithelial cell. An electron dense band was found at the attachment site between the Cryptoporidium and the host cell. At the attachment site,the cytoplasma membrane of Cryptosporidium appeared in the form of many membranous folds,and contacted closely with the plasma membrane of the epithelial cell. Rhoptry-like structure and small electron dense granules were found in the merozoite,but their effects on the development of Cryptosporidium ar?still unknown (Figs. 1 - 5).