Mechanisms of kindling induced by norbornan intoxication |
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| Authors: | A I Golovko M B Ivanov O A Sviderskii G A Sofronov V V Shilov |
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| Institution: | (1) Department of Military Toxicology and Medical Protections, Laboratory of Perfluorocarbons, Military Medical Academy, St. Petersburg |
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| Abstract: | Single injection of norbornan induced kindling by disordering postsynaptic GABAergic structures. Modulation of GABAA receptor chlorine ionic channels is most crucial, while disturbances in postsynaptic low-affinity GABAA receptors are less important for this phenomenon. It is unlikely that GABAB, dopamine, and muscarinic neurotransmitter structures are involved into this process.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 6, pp. 653–656, June, 1998 |
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| Keywords: | norbornan kindling |
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