| 局部进展期直肠癌新辅助治疗后器官保留策略进展 |
| |
| 引用本文： | 赵莹,唐源,金晶.局部进展期直肠癌新辅助治疗后器官保留策略进展[J].中华放射肿瘤学杂志,2022,31(2):208-213. |
| |
| 作者姓名： | 赵莹 唐源 金晶 |
| |
| 作者单位： | 国家癌症中心/国家肿瘤临床医学研究中心/中国医学科学院北京协和医学院肿瘤医院放疗科,北京 100021 |
| |
| 基金项目： | 首都卫生发展科研专项(2020-1-4021);中央高校基本科研业务费专项(3332019055);首都临床特色应用研究专项(Z181100001718136)。 |
| |
| 摘 要： | 新辅助放化疗联合全直肠系膜切除术为分期T
3-T
4期或N+的局部进展期直肠癌(LARC)的标准治疗，但往往会带来一系列术后并发症，尤其是接受腹会阴联合直肠癌根治术(Mile′s术)不能保留肛门者，严重影响生活质量。对于新辅助治疗后肿瘤(近)临床完全缓解者，器官保留策略在与根治性手术达到相似治疗疗效...
|
| 关 键 词： | 直肠癌 器官保留 临床完全缓解 等待观察 |
| 收稿时间： | 2020-05-15 |
Advances in organ preservation for locally advanced rectal cancer after neoadjuvant chemoradiotherapy |
| |
| Zhao Ying,Tang Yuan,Jin Jing.Advances in organ preservation for locally advanced rectal cancer after neoadjuvant chemoradiotherapy[J].Chinese Journal of Radiation Oncology,2022,31(2):208-213. |
| |
| Authors: | Zhao Ying Tang Yuan Jin Jing |
| |
| Institution: | Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China |
| |
| Abstract: | Neoadjuvant chemoradiotherapy combined with total mesorectal excision is the standard treatment for stage T3-T4/N+locally advanced rectal cancer(LARC).However,proctectomy is burdened with consistent postoperative morbidity,severely affecting the quality of life.“Organ preserving”methods could achieve similar oncological outcomes in highly selected patients whose tumors demonstrate(almost)clinical complete response to neoadjuvant treatment,while maintaining the quality of life and anorectal function by keeping the anus.This article aims to summarize the strategies of organ preservation after neoadjuvant treatment of LARC,salvage treatment for regrowth or recurrence,and anorectal function after organ preservation strategies. |
| |
| Keywords: | Rectal neoplasm Organ preservation Clinical complete response Watch and wait |
| 本文献已被 维普 等数据库收录！ |
| 点击此处可从《中华放射肿瘤学杂志》浏览原始摘要信息 |
| 点击此处可从《中华放射肿瘤学杂志》下载免费的PDF全文 |
