Antiulcerogenic Activity of Ethanolic Leaf Extract of Lasianthera Africana |
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| Authors: | Jude E Okokon Bassey S Antia Emem E Umoh |
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| Affiliation: | 1Department of Pharmacology and Toxicology, University of Uyo, Uyo, Nigeria;2Department of Chemistry, University of Uyo, Uyo, Nigeria |
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| Abstract: | The effect of ethanolic leaf extract of Lasianthera africana on experimentally induced ulcer was studied in rats. The extract (1000 – 3000mg/kg) inhibited ethanol-induced, indomethacin - induced and reserpine -induced ulcer models in a dose dependent fashion. The various degrees of inhibitions were statistically significant (p<0.01). The effect of the extract was comparable to that of the standard drugs used. Thus, Lasianthera africana extract demonstrated a good antiulcer activity which supports the antiulcer effect of this plant in traditional medicine. |
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| Keywords: | Lasianthera africana antiulcer vegetable |
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