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Varicella zoster virus in health care workers in northern Israel: seroprevalence and predictive value of history of varicella infection
Authors:Chazan Bibiana  Colodner Raul  Teitler Nava  Chen Yael  Raz Raul
Institution:aInfectious Diseases Unit, Ha'Emek Medical Center, Afula, Israel;bFamily Medicine Department, North Branch Ben Gurion University, Israel;cClinical Microbiology Laboratory, Ha'Emek Medical Center, Afula, Israel;dInfectious Diseases Unit, Western Galilee Medical Center, Nahariya, Israel;eRappaport Faculty of Medicine, Technion Haifa, Israel
Abstract:Health care workers (HCWs) are susceptible to hospital acquired varicella zoster virus (VZV). We evaluated seroprevalence and predictive value of a history of varicella disease (VD) with VZV serology in HCWs in northern Israel. A total of 200 HCWs were enrolled. A high rate of seropositivity for VZV-IgG was found: 98.5% seropositive and only 1.5% seronegative. A positive history of VD was an excellent predictor for the presence of VZV-IgG; however, a negative history of VD does not rule out the presence of VZV-IgG.
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