四氧化三铁微粒与碘化油混悬液栓塞肝癌血管的疗效

目的:研究四氧化三铁微粒与碘化油混悬液对原发性肝癌供瘤血管的影响。方法:对98例经导管肝动脉化疗栓塞术(TACE)治疗的原发性肝癌患者进行回顾性的研究。栓塞方法分为3组:A组(碘化油+化疗药物的混悬液),B组(碘化油+化疗药物的混悬液+明胶海绵)和C组(碘化油+化疗药物+四氧化三铁微粒的混悬液)。比较栓塞后供瘤血管再通情况。结果:B组与C组的血管未再通率明显高于A组(P<0.01),而部分再通率及完全再通率明显低于A组(P<0.01);B组与C组的血管再通率比较差异无统计学意义(P>0.05)。结论:栓塞后肿瘤供瘤血管再通与所用栓塞方法有关,四氧化三铁微粒与碘化油混悬液对肝癌患者进行栓塞治疗是一种更有效的方法。

Therapeutic Effect of Embolizing Hepatoma Vascellum Using the Suspension of Ferroso-Ferric Oxide Granules and Iodinated Oil

Objective: To investigate the effect of using the suspension of ferroso-ferric oxide granules and iodinated oil to embolize the artery of primary hepatic carcinoma.Methods: Ninety-eight cases with primary hepatic carcinoma who had accepted TACE were retrospectively studied and were divided into three groups according to the method of treatment as group A(suspension of iodinated oil embolism and chemotherapeutics),group B(suspension of iodinated oil embolism,chemotherapeutics,and the stem artery embolizing by spongia gelatinosa),and group C(suspension of ferroso-ferric oxide granules iodinated oil and chemotherapeutics).Results: The nulli-recanalization rate of group B and group C were obviously higher than that of group A(both P<0.01),however,the part-recanalization rate and the all-recanalization rate of group A and B were lower(all P<0.01).There was no statistical differences in recanalization between group B and group C(P>0.05).Conclusion: After embolization,the revascularization results were different according to the embolizing method adopted.The method of using the suspension of ferroso-ferric oxide granules and iodinated oil is the more effective one.