急性高脂血症性胰腺炎临床特征分析

目的:探讨急性高脂血症性胰腺炎(AHP)的临床特点以加深对该疾病的认识。方法:将本院2003年1月至2008年12月收治的133例急性胰腺炎(AP)根据病因分为急性胆源性胰腺炎(ABP)76例、AHP 29例、酒精性胰腺炎10例和其他18例。对AHP与ABP的临床特征进行比较,并分析高脂血症(HL)与AP的相关性。结果:临床评分相同情况下,AHP在脂肪肝发生率、糖尿病发生率、重症急性胰腺炎和血脂方面高于ABP,在血清淀粉酶和肝功能受损方面均低于ABP,差异均有统计学意义(P<0.05)。甘油三酯与CT严重程度评分(CTSI)分级相关。结论:AHP具有病情重、血脂高和血清淀粉酶低等不同于一般急性胰腺炎的临床特征,回顾分析其临床资料有利于加深对AHP的认识并指导临床诊疗。

Clinical Analysis of Acute Hyperlipidemic Pancreatitis

Objective: To study the clinical characteristics of acute hyperlipidemic pancreatitis(AHP).Methods: A total of 133 patients suffering from acute pancreatitis in our hospital from January 2003 to December 2008 were divided into four groups according to the causes as acute biliary pancreatitis(ABP,n=76 cases),acute hyperlipidemic pancreatitis(AHP,n=29 cases), alcoholic pancreatitis(AP,n=10 cases),and others(n=18 cases).The clinical characteristics in ABP group and AHP group were compared.The correlation between hyperlipoidemia(HL) and AP was analyzed.Results: With the same clinical markers,the adiposis hepatica incidence,diabetes mellitus incidence,severe acute pancreatitis scoring(CT severity index,CTSI) and blood-lipid in AHP group were higher than those in ABP group(all P<0.05).However,serum amylase and liver function damage in AHP group were lower than those in ABP group(both P<0.05).CTSI was correlated with plasma TG.Conclusion: AHP is different from general AP because it is severer with higher blood-lipid level and low serum amylase level.