Enteric fever in India: current scenario and future directions |
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Authors: | L. E. B. Nabarro B. Veeraraghavan P. Rupali |
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Affiliation: | 1. Department of Infectious Disease, Christian Medical College, Vellore, India;2. Public Health England, London, UKDS and LEBN contributed equally to this work.;3. Department of Microbiology, Christian Medical College, Vellore, India |
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Abstract: | Enteric fever is a major cause of morbidity and mortality in tropical areas worldwide. The Indian subcontinent bears the brunt of the disease, both in terms of absolute case numbers and drug‐resistant strains. Recent phylogenetic studies suggest that the multidrug‐resistant clade H58 originated in India and subsequently expanded through Asia and Africa. In Africa, it caused unrecognised outbreaks in areas previously considered free of the disease. In this study, we discuss the current status of enteric fever in India, the factors preventing its control and its future directions in this rapidly developing nation. |
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Keywords: | enteric typhoid paratyphoid India drug resistance azithromycin enté rique typhoï de paratyphoï de Inde ré sistance aux mé dicaments azithromycine enté rica tifoidea paratifoidea India resistencia a medicamentos azitromicina |
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